Pearl vs Overjet: which dental imaging AI fits your practice?
Pearl leads our imaging rankings (Overjet 8.6, Pearl 8.9): choose Pearl if chairside case acceptance is the priority, and choose Overjet if you need consistent, quantified findings across many providers and locations. Overjet holds 12 FDA clearances we verified to Pearl's 8, and also sells imaging software and insurance verification.
· Independently reviewed by Dental AI Tools
At a glance
| Attribute | Overjet🇺🇸 | Pearl (Second Opinion)🇺🇸 |
|---|---|---|
| Score | 8.6/10 | 8.9/10 |
| Category rank | #3 of 18 in Imaging | #1 of 18 in Imaging |
| Verdict | FDA-cleared AI for x-ray detection and quantification, popular with DSOs; 2026 clearances added image-quality checks and multi-image caries charting. | FDA-cleared AI radiograph detection for chairside case acceptance, plus Pearl Voice ambient notes and voice perio charting (launched April 2026). |
| Pricing | Contact vendor | Contact vendor |
| Website | overjet.com | hellopearl.com |
FDA clearances: Overjet 12, Pearl (Second Opinion) 8
From our FDA-cleared dental AI tracker, verified against the FDA database on October 28, 2026.
| Tool | Device | FDA number | Cleared |
|---|---|---|---|
| Overjet | Overjet Multi-Image Caries and Charting Assist | K261059 | 2026-08-06 |
| Overjet | Overjet Iris Intelligent Imaging System | K253930 | 2026-04-10 |
| Overjet | Overjet CBCT Assist | K251514 | 2025-12-05 |
| Pearl (Second Opinion) | Second Opinion Panoramic | K250525 | 2025-11-14 |
| Pearl (Second Opinion) | Second Opinion CS | K243234 | 2025-06-12 |
| Pearl (Second Opinion) | Second Opinion 3D | K243989 | 2025-05-23 |
| Pearl (Second Opinion) | Second Opinion BLE | K243230 | 2025-05-09 |
| Pearl (Second Opinion) | Second Opinion Pediatric | K243893 | 2025-05-05 |
| Pearl (Second Opinion) | Second Opinion Periapical Radiolucency Contours | K242600 | 2025-04-11 |
| Pearl (Second Opinion) | Second Opinion CC | K242522 | 2025-01-16 |
| Overjet | Overjet Image Enhancement Assist | K241681 | 2024-09-09 |
| Overjet | Overjet Charting Assist | K241684 | 2024-08-27 |
| Overjet | Overjet Caries Assist-Pediatric | K233738 | 2024-03-04 |
| Overjet | Overjet Charting Assist | K233590 | 2024-02-23 |
| Overjet | Overjet Periapical Radiolucency Assist | K231678 | 2023-09-21 |
| Overjet | Overjet Caries Assist | K222746 | 2023-03-27 |
| Overjet | Overjet Calculus Assist | K220928 | 2022-12-16 |
| Overjet | Overjet Caries Assist | K212519 | 2022-05-10 |
| Pearl (Second Opinion) | Second Opinion | K210365 | 2022-03-04 |
| Overjet | Overjet Dental Assist | K210187 | 2021-05-19 |
Same score, different jobs
A tie means both tools are strong on evidence, detection scope, integrations and patient communication. It doesn't mean they solve the same problem, so compare them against your own workflow.
Pearl (Second Opinion)
Pearl is built around the moment you turn the screen toward the patient. Second Opinion analyzes bitewing and periapical x-rays and highlights findings such as caries, calculus, margin discrepancies and periapical radiolucencies. The clinician reviews the color overlays, then uses the patient view and take-home report to explain the diagnosis.
- FDA clearance: Second Opinion (K210365, 2022) and Second Opinion Pediatric (K243893, 2025).
- Integrations: Pearl lists 40+ integrations with imaging and practice systems.
- Pearl reports a 30% average lift in case acceptance. That's vendor-reported, and we haven't verified it.
Overjet
Overjet's Vision AI detects and outlines disease and anatomy on x-rays. Overjet positions it for the daily huddle and insurance submissions as well as the chairside conversation, with the goal of consistent diagnosis across providers.
- FDA clearances: bone-level measurement (K210187), caries detection (K222746) and multi-image caries and charting (K261059, 2026).
- Platform: Overjet also sells IRIS imaging software, insurance verification (1,000+ payers) and a voice documentation suite.
- DSO testimonials on its site are the vendor's, not ours.
Questions to ask before you decide
- Is case acceptance your biggest gap? Ask to see Pearl's patient view and take-home report.
- Do you need consistent, quantified findings across several locations, or imaging software and insurance verification from one vendor? Ask Overjet to show those workflows.
- Is your imaging system on each vendor's supported list, and who on your team will review the AI findings each day?
FAQ
Which is better, Pearl or Overjet?
Overjet scores 8.6/10 and Pearl 8.9/10 in the Dental AI Tools (dentalaitools.com) imaging rankings. Pearl fits practices focused on chairside case acceptance; Overjet fits groups and DSOs that want consistent, quantified findings across providers.
How many FDA clearances do Pearl and Overjet have?
In our FDA tracker, Overjet holds 12 FDA 510(k) clearances and Pearl holds 8, each verified in the FDA database and listed with its K-number at https://dentalaitools.com/fda-cleared-dental-ai
Do Pearl and Overjet serve DSOs?
Yes, both serve DSOs. Overjet positions itself around consistency across providers and locations and also sells imaging software and insurance verification. Pearl says it serves single offices through DSOs that want consistent diagnostic criteria.
How much do Pearl and Overjet cost?
Neither publishes pricing. Ask whether the quote is per location, per provider or per module, and get any add-ons quoted separately.
Get new comparisons and score changes every Tuesday
The Dental AI Spotlight email lands every Tuesday with new head-to-head comparisons, score changes and FDA updates, including any change to Overjet or Pearl (Second Opinion).
Get the Tuesday email →Sources
- https://www.accessdata.fda.gov/cdrh_docs/pdf22/K222746.pdf
- https://www.accessdata.fda.gov/cdrh_docs/pdf24/K243893.pdf
- https://www.accessdata.fda.gov/cdrh_docs/pdf26/K261059.pdf
- https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfPMN/pmn.cfm?ID=K210187
- https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfPMN/pmn.cfm?ID=K210365
- https://www.hellopearl.com
- https://www.overjet.com
- newsletter:issue-1 (The 8.8 tie: Pearl vs Overjet, 2026-10-20)
Related comparisons
Other tools to consider
- Videa🇺🇸 8.8/10 · Imaging
- DEXIS (DTX Studio Clinic)🇺🇸 8.5/10 · Imaging
- DentalMonitoring🇫🇷 8.2/10 · Imaging
- Diagnocat🇺🇸 7.8/10 · Imaging
- uLab Systems🇺🇸 7.8/10 · Imaging
alphaSource Consulting helps practices and DSOs choose and roll out dental AI.
Talk to alphaSource Consulting →One email every Tuesday.
By subscribing, you agree to get the Dental AI Spotlight newsletter by email every Tuesday, plus occasional updates from Dental AI Tools. Unsubscribe anytime with one click.
Scores are editorial, and no tool we score can be a sponsor. How we score